Cell Models and Synaptic Physiology

Anatomy tells you who connects to whom. Physiology tells you what those connections do. These two lessons build the biophysical parameter database that turns a wiring diagram into a simulation. Lesson 09 — Synaptic Physiology A SynapseModel database covering 6 neurotransmitter types: Reversal potentials — what voltage each synapse drives toward Receptor kinetics — rise time, decay time, conductance amplitude Confidence levels — distinguishing measured values from literature estimates from educated guesses Each parameter carries provenance: where it came from, how reliable it is, what the fly-specific evidence says versus the generic insect value. ...

February 25, 2026 · 1 min · A Human-Machine Collaboration